Given the large proportion of disenchant glyphs and outright hostile debuff glyphs (-5/-3 on my primary attack, -2 defence and a vulnerability, all from one glyph. I mean come on!), I am avoiding the glyphs entirely. Which is a pity, since it means they may as well not be there. All they are now is a hazard to navigation.
I tried finding a pattern in terms of appearance, position or location, but they appear totally random. At least with scrolls and potions you have a slight idea of whether or not they're detrimental.
So is everyone else just avoiding them too? Or am I missing something here?